Bioconductor Case Studies by Florian Hahne, Robert Gentleman, Seth Falcon, Wolfgang Huber

Bioconductor Case Studies



Download Bioconductor Case Studies




Bioconductor Case Studies Florian Hahne, Robert Gentleman, Seth Falcon, Wolfgang Huber
Language: English
Page: 296
Format: pdf
ISBN: 0387772391, 9780387772394
Publisher: Springer

Bioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in contemporary molecular biology. In this volume, the authors present a collection of cases to apply Bioconductor tools in the analysis of microarray gene expression data. Topics covered include

* import and preprocessing of data from various sources

* statistical modeling of differential gene expression

* biological metadata

* application of graphs and graph rendering

* machine learning for clustering and classification problems

* gene set enrichment analysis

Each chapter of this book describes an analysis of real data using hands-on example driven approaches. Short exercises help in the learning process and invite more advanced considerations of key topics. The book is a dynamic document. All the code shown can be executed on a local computer, and readers are able to reproduce every computation, figure, and table.

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